Lixoft Monolix Suite 2019 R1 (macOS/Lnx) | 111/69 Mb
Monolix is the most advanced and simple solution for non-linear mixed effects modeling (NLME) for pharmacometrics. It is based on the SAEM algorithm and provides robust, global convergence even for complex PK/PD models. Monolix is used for preclinical and clinical population PK/PD modeling and for Systems Pharmacology. Monolix enjoys a large user community. Monolix is widely used by academia, the pharmaceutical industry as well as the US regulatory agencies.

Advanced Statistical Methodologies
Reliable convergence for all type of data is a                                                                                                                            centerpiece in population PKPD modeling, which is why Lixoft pioneered in collaboration with Inria the SAEM algorithm.
Automated generation of diagnostic tests
Monolix automatically generates a full set of diagnostic Descriptions even for complex PK/PD models. For example, you can instantaneously create the Visual Predictive Check, split by any patient subgroup you would want to investigate.
Increased productivity and quality
Efficient C++ solver package, standardized model language with Mlxtran, PK/PD model library and integrated software all contribute to better productivity and quality.
Very easy to use with its GUI
Our solutions are designed for ease of use. Monolix can be used via a graphical interface or command lines for powerful scripting. This means less programming for you and more focus on exploring models and pharmacology to deliver in time to your customers.
Minimum system requirements
Architecture: 64 bits
1GB RAM or above
Xcode to be able to compile any C++ code  on your computer.
XQuartz
Optimally standard screen resolution not less than 800x600 pixels is recommended.
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https://lixoft.com/

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